Baby with scan helmet on

The Need

Brain development at the beginning of life and brain degeneration at the end of life are both areas where specialised care is required.

Understanding the vulnerabilities at the extremes of age will allow for better care in both young and old people.

Challenges associated with infant brain development include prematurity, accquired brain injury, and genetic disorders. Hospitalization can negatively impact parental interactions, compounding long-term effects.

Elderly medicine is associated with frailty, co-morbidities, and the need for integration with social care. Providing more support for care within communities helps support independence in aging populations and keeps the brain active and healthy for longer.

Baby with scan helmet on

Issues associated with neonates and infants include prematurity, developmental and genetic disorders, and barriers to parental contact during hospitalisation, all of which can cause long-term brain injury.

Elderly medicine is associated with frailty, co-morbidities, and the need for integration with social care. Providing more support for care within communities helps support independence in ageing populations and keeps the brain active and healthy for longer.

The Need

Brain development at the beginning of life and brain degeneration at the end of life are both important areas where specialised care is required.

Understanding the vulnerabilities at the extremes of age will allow for better care in both young and old patients.

How can we help?

We hope to support both ends of the age spectrum by improving care pathways and supporting innovations.

For neonatal care, this includes:

  1. Improving pathways and evaluation of the importance of baby-parent contact.
  2. New technology in neonatal monitoring, including seizure detection and ongoing commercialisation of the NeWTS wireless monitoring in intensive care.
  3. Expansion of the genomic screening for the diagnosis of rare childhood diseases.

For elderly medicine, this includes:

  1. Improving recognition, treatment and ongoing care of under-diagnosed, treatable conditions in the elderly, such as cervical myelopathy and idiopathic normal pressure hydrocephalus.
  2. Reducing the need for elderly people to visit hospital by developing community alternatives to delivering neurological rehabilitation, such as telerehabilitation and providing these to homes and local care facilities.

The Team

Professor Topun Austin
Professor Topun AustinTheme Lead
Professor Topun Austin is a Consultant Neonatologist and Director of neoLAB based at the Evelyn Perinatal Imaging Centre at The Rosie Hospital Cambridge. His main research interests are in brain development and injury in the newborn, and in the development of novel monitoring and imaging technologies. He has active collaborations with the Department of Medical Physics and Biomedical Engineering at UCL and Nanyang Technological University in Singapore, through which he is investigating the role of sleep and early mother-infant interactions on brain development, consciousness and cognition.
Professor David Rowitch
Professor David RowitchCo-theme Lead
Professor David Rowitch is Professor of Paediatrics at the University of Cambridge and Consultant Neonatologist at Addenbrookes Hospital. His main research focus is developmental neuroscience and neuronal-glial interactions. He is world-leading expertise in brain developmental biology, clinical interventions for neonatal brain injury, and rare neurological disorders, including establishing a platform for whole genome sequencing in specific genetic conditions.

Projects